Alpha Arbutin has a similar structure as tyrosine (a non-essential amino acid that binds with tyrosinase to catalyze melanin synthesis). Due to its perfect affinity for active sites of tyrosinase Alpha Arbutin blocks tyrosine.

It is thereby inhibiting melanin production without affecting cell viability, unlike Kojic Acid, which decreases tyrosine production and can be cytotoxic. Alpha Arbutin present in this serum has a very low IC50 value (IC50 is a measure of the potency of the compound in inhibiting a biochemical function. Low value means even less concentration of active is effective and more potent).

It is scientifically proven to show effects even at lower concentrations. Also, every Arbutin is not the same. Beta Arbutin, commonly used in Arbutin serums, is cheap and less effective. According to the AAD, when you stop what is causing dark spots and protect your skin from damage by UV rays, then fading is effective and fast.

This serum exhibits both anti-pigmentation and anti-tanning after UV exposure, resulting in an even bright skin tone. However, it is not meant for use as a fairness treatment or sunblock.

It is one of safest and effective skin lightening active compared to other actives such as Kojic Acid used in traditional pigmentation removal cream. It inhibits melanin production without causing cell cytotoxicity thus is safe to be used as anti-pigmentation daily serum for longer durations unlike other skin lightening or brightening ingredients.